Ovarian Hypofunction

It is the reduction of the function of the ovaries (includes the decreased production of hormones).

Alternative names

Premature ovarian failure; Insufficiency of the ovaries.

Signs and Symptoms

Women with ovarian hypofunction may have symptoms of menopause, such as:

• Hot flushes
• Irregular or absent menstrual periods
• Changes in mood
• Cold sweats
• Vaginal dryness

Ovarian hypofunction can also cause a woman difficulty in getting pregnant.

Causes

• Ovarian hypofunction can be caused by genetic factors, such as chromosomal abnormalities. It can also occur with certain autoimmune disorders that alter the normal function of the ovaries.
• Radiation therapy and chemotherapy may also lead to ovarian hypofunction.

Risk Factors

• Irregular menstrual cycle
• Infertility

When to contact a medical professional?

Check with the provider if:

• You no longer have menstrual periods.
• If you have symptoms of premature menopause.
• If you have difficulty in getting pregnant.

Diagnosis

• A blood test will be done to check the level of the follicle-stimulating hormone (FSH). The levels of this hormone are higher than normal in women with ovarian hypofunction.
• Other blood tests may be done to look for autoimmune disorders or thyroid disease.
• Women with ovarian hypofunction who wish to become pregnant may be concerned about their ability to conceive. Women under 30 can undergo chromosomal analysis to look for problems. Older women approaching menopause in most cases do not need this test.

Treatment and Management

• Frequently, estrogen therapy helps alleviate the symptoms of menopause and prevents bone loss; however, it does not increase the chances of getting pregnant.
• Perform medication and exercise daily.
• Have a healthy diet rich in vitamin and mineral.