Bone Marrow Transplantation is one of the most novel organ transplant procedures that provides treatment and cure for blood cancer, leukemia and other blood disorders such as sickle cell anemia and thalassemia. It is the latest procedure in which the healthy bone marrow cells from a donor are infused into a diseased patient whose bone marrow cells have depleted or are not working. Bone marrow cells are responsible for the production of cells that constitute our immune system. Malfunctioning weakens our immune system and its response, making us susceptible to numerous diseases and complications. Bone marrow transplants may use cells from your own body (autologous transplant) or from a donor (allogeneic transplant).
When is Bone Marrow Transplant recommended?
Bone marrow transplants can benefit people with a variety of both cancerous (malignant) and noncancerous (benign) diseases, including:
- Acute leukemia
- Aplastic anemia
- Bone marrow failure syndromes
- Chronic leukemia
- Hodgkin’s lymphoma
- Immune deficiencies
- Inborn errors of metabolism
- Multiple myeloma
- Myelodysplastic syndromes
- Non-Hodgkin’s lymphoma
- Plasma cell disorders
- POEMS syndrome
- Primary amyloidosis
What are the types of Bone Marrow Transplants?
Allogenic Bone Marrow Transplantation: This bone marrow transplantation includes the introduction of the healthy bone marrow cells from a donor into a patient. This type of transplantation is done when the patient’s bone marrow cells are damaged and need to be replaced. The bone marrow cells from the donor are collected from the blood of the donor, umbilical cord or from the hip bone. The patient’s own cells need to be destroyed that the body can accept all cells of the donor. The patient is exposed to radiation therapy or chemotherapy.
Post this type of transplantation you are t be kept under close observation to ensure that there are no rejections from your system.
Autologous Bone Marrow Transplantation: It can be defined as the process in which healthy cells from one part of the patient’s body are introduced into the bone marrow to replace the diseased or damaged bone marrow cells. This type of transplant has an advantage over the allogenic as one doesn’t need to bother about the rejection from the body. An autologous stem cell transplant might be an option if your body is producing enough healthy bone marrow cells. Those cells can be collected, frozen and stored for later use. In this type also your existing bone marrow cells may have to be destroyed hence you may be given radiotherapy and chemotherapy.
Paras Healthcare and Paras Cancer Centre specializes in providing affordable Bone Marrow Transplant procedure. The team of hematologists and cancer specialists specialize in performing both types of Bone Marrow Transplant – Allogenic Bone Marrow Transplantation and Autologous Bone Marrow Transplantation.